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Seizures During Stroke Thrombolysis Heralding Dramatic Neurologic Recovery Neurol 67:2048-2049, Rodan,L.H.,et al, 2006 See this aricle in Pubmed Article Abstract Seizures during thrombolytic therapy for ischemic stroke have not previously been described as a favorable prognostic sign. We report three patients with severe stroke (NIH Stroke Scale [NIHSS] score 15 to 20) who experienced a seizure during tissue plasminogen activator (tPA) infusion. While initially raising alarm about possible hemorrhage, the seizures heralded dramatic recovery (an immediate 15-point NIHSS score improvement after tPA; NIHSS score 0 or 1 at 24 hours). We propose that the seizures during thrombolysis may indicate cortical reperfusion and/or hyperperfusion due to early recanalization of an acutely occluded intracranial artery.

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(click to filter results - removes previous filter) cerebrovascular accident cerebrovascular accident,seizure with cerebrovascular accident,thrombolytic agents in treatment cerebrovascular accident,thromobolytic agents in treatment,early dramatic recovery fibrinolytic agents fibrinolytic agents,complications heralding manifestation recanalization,arterial reperfusion seizure

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